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Party Message Board > Why does Malegra DXT Plus affect nitric oxide ?
Why does Malegra DXT Plus  affect nitric oxide  ?
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kirazmattson
437 posts
Apr 01, 2025
1:04 AM
Malegra DXT Plus is a combination medication that contains sildenafil (the active ingredient in Viagra), dapoxetine, and sometimes other ingredients. The primary action of sildenafil is related to nitric oxide (NO) levels in the body, which is why Malegra DXT Plus can affect these levels. Here’s how Malegra DXT Plus influences nitric oxide levels: Sildenafil and Nitric Oxide: Sildenafil works by inhibiting the enzyme phosphodiesterase type 5 (PDE5). This enzyme normally breaks down cyclic guanosine monophosphate Malegra DXT Plus that plays a key role in dilating blood vessels. cGMP is produced when nitric oxide (NO) is released in response to sexual stimulation. Nitric oxide is a vasodilator, meaning it relaxes and widens the blood vessels, improving blood flow. By inhibiting PDE5, sildenafil increases the levels of cGMP, which helps maintain the effects of nitric oxide. This leads to improved blood flow to the penis, facilitating an erection in men with erectile dysfunction. Dapoxetine's Role: Dapoxetine, on the other hand, is primarily a selective serotonin reuptake inhibitor (SSRI) that is used to treat premature ejaculation. While its primary mechanism doesn’t directly relate to nitric oxide, by prolonging the time to ejaculation, it allows for more time to experience the effects of nitric oxide in the body during sexual activity. This indirect influence can help individuals with premature ejaculation to enjoy a more stable sexual experience, indirectly allowing better control over the sexual response.


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